TY - GEN
T1 - Intrastromal refractive surgery by ultrashort laser pulses:
T2 - BIOS 2000 The International Symposium on Biomedical Optics
AU - Heisterkamp, Alexander
AU - Maatz, Gero
AU - Ripken, Tammo
AU - Lubatschowski, Holger
AU - Welling, Herbert
AU - Luetkefels, Elke
AU - Drommer, Wolfgang
AU - Ertmer, Wolfgang
PY - 2000/6/7
Y1 - 2000/6/7
N2 - The Feasibility of refractive surgery with ultrashort laser pulses in the fs-regime was studied. The Experiments were performed with an Erbium fibrelaser oscillator, which was amplified by means of chirped pulse amplification in a Titanium-Sapphire regenerative amplifier. With this system pulse durations of 180 fs and pulse energies of up to some hundred μJ were possible. The photodisruption was performed in corneal tissue in order to create corneal incisions and lamellars. Surface quality and thermal damages of the cuts inside the tissue were studied with the help of micromorphological analysis, such as scanning electron microscopy (SEM) and histological sections. High level precision along with minimal thermal damage could be observed. Saline solution as a model substance was used for studying side effects as bubble formation and pressure transients. The pressure measurements were performed using broadband acoustic transducers. Gas bubbles were analysed with respect to formation, dynamics, interaction and composition of different gas constituents with the help of flash photography and gas chromatography. The results demonstrate the minimal invasive treatment of corneal stroma by fs-photodisruption. Studies of secondary effects indicate, that additional processes have to be considered.
AB - The Feasibility of refractive surgery with ultrashort laser pulses in the fs-regime was studied. The Experiments were performed with an Erbium fibrelaser oscillator, which was amplified by means of chirped pulse amplification in a Titanium-Sapphire regenerative amplifier. With this system pulse durations of 180 fs and pulse energies of up to some hundred μJ were possible. The photodisruption was performed in corneal tissue in order to create corneal incisions and lamellars. Surface quality and thermal damages of the cuts inside the tissue were studied with the help of micromorphological analysis, such as scanning electron microscopy (SEM) and histological sections. High level precision along with minimal thermal damage could be observed. Saline solution as a model substance was used for studying side effects as bubble formation and pressure transients. The pressure measurements were performed using broadband acoustic transducers. Gas bubbles were analysed with respect to formation, dynamics, interaction and composition of different gas constituents with the help of flash photography and gas chromatography. The results demonstrate the minimal invasive treatment of corneal stroma by fs-photodisruption. Studies of secondary effects indicate, that additional processes have to be considered.
UR - https://www.scopus.com/pages/publications/0033720694
U2 - 10.1117/12.387518
DO - 10.1117/12.387518
M3 - Conference contribution
AN - SCOPUS:0033720694
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 146
EP - 156
BT - Ophthalmic Technologies X
PB - SPIE
Y2 - 22 January 2000 through 28 January 2000
ER -