The asymmetric vinylogous mukaiyama aldol reaction

Martin H. C. Cordes; Markus Kalesse

doi:10.1002/0471264180.or098.02

The asymmetric vinylogous mukaiyama aldol reaction

Martin H. C. Cordes, Markus Kalesse^*

^*Korrespondierende*r Autor*in für diese Arbeit

Institut für Organische Chemie

Publikation: Beitrag in Fachzeitschrift › Artikel › Forschung › Peer-Review

Abstract

The vinylogous Mukaiyama aldol (VMA) reaction allows efficient access to larger segments for complex natural product synthesis, primarily polyketides, through the construction of vicinal hydroxyl and methyl groups as well as di- and tri-substituted double bonds in a single operation. In this chapter, the current scope and limitations of this transformation, as well as its application in natural product synthesis, are discussed.

Originalsprache	Englisch
Seiten (von - bis)	173-774
Seitenumfang	602
Fachzeitschrift	Organic Reactions
Jahrgang	98
DOIs	https://doi.org/10.1002/0471264180.or098.02
Publikationsstatus	Veröffentlicht - 11 März 2019

ASJC Scopus Sachgebiete

Physikalische und Theoretische Chemie
Organische Chemie

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10.1002/0471264180.or098.02

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