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Extending the Measurement Range in Ophthalmic Linear Optical Coherence Tomography using Dual Reference Path Interferometry

  • Niklas Bauer*
  • , David Harings
  • , Damian Mendroch
  • , Jan Matrisch
  • , Uwe Oberheide
  • , Alexander Heisterkamp
  • *Corresponding author for this work

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Abstract

A fiber-based linear optical coherence tomography (LOCT) system employing a cost-effective CMOS camera has previously demonstrated high-resolution imaging suitable for retinal screening, including glaucoma monitoring. However, the system’s imaging depth was constrained to approximately 400 µm, insufficient for depth imaging of the optic nerve head (ONH), due to limitations imposed by the camera’s sensor size and pixel pitch. To overcome this limitation without replacing the economical and available sensor, we present a modification to the reference arm. By optimizing the utilization of the camera sensor’s vertical dimension, the system achieves an extended imaging depth, enabling the visualization of deeper tissue structures. Validation using an artificial eye model confirms that the modified LOCT system significantly enhances imaging depth while maintaining B-Scan quality. This advancement offers a cost-effective approach to extend the measurement range of LOCT systems, broadening their applicability in retinal imaging without altering the actual imaging sensor.

Original languageEnglish
Title of host publicationOphthalmic Technologies XXXV
EditorsDaniel X. Hammer, Derek Nankivil, Yuankai K. Tao
PublisherSPIE
ISBN (Electronic)9781510683488
DOIs
Publication statusPublished - 19 Mar 2025
EventSPIE Photonics West BiOS 2025 - San Francisco, United States
Duration: 25 Jan 202531 Jan 2025

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume13300
ISSN (Print)1605-7422

Conference

ConferenceSPIE Photonics West BiOS 2025
Abbreviated titleBiOS 2025
Country/TerritoryUnited States
CitySan Francisco
Period25 Jan 202531 Jan 2025

Keywords

  • LOCT
  • Low-cost OCT
  • OCT
  • Retinal Imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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