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Fungi as chemical industries and genetic engineering for the production of biologically active secondary metabolites

  • Abid Ali Khan*
  • , Nafees Bacha
  • , Bashir Ahmad
  • , Ghosia Lutfullah
  • , Umar Farooq
  • , Russell John Cox
  • *Corresponding author for this work

Research output: Contribution to journalReview articleResearchpeer review

Abstract

Fungi is somewhere in between the micro and macro organisms which is a good source of producing biologically active secondary metabolites. Fungi have been used as tool for producing different types of secondary metabolites by providing different nutrients at different laboratory conditions. The fungi have been engineered for the desired secondary metabolites by using different laboratory techniques, for example, homologous and heterologous expressions. This review reported how the fungi are used as chemical industry for the production of secondary metabolites and how they are engineered in laboratory for the production of desirable metabolites; also the biosynthetic pathways of the bio-organic-molecules were reported.

Original languageEnglish
Pages (from-to)859-870
Number of pages12
JournalAsian Pacific Journal of Tropical Biomedicine
Volume4
Issue number11
DOIs
Publication statusPublished - 1 Jan 2014
Externally publishedYes

Keywords

  • Chemical biology
  • Fungi
  • Microbiology
  • Molecular genetics
  • Natural products

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (miscellaneous)

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