Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives

Torsten Busch; Gerald Dräger; Eike Kunst; Hannah Benson; Florenz Sasse; Karsten Siems; Andreas Kirschning

doi:10.1039/c6ob01697a

Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives

Torsten Busch, Gerald Dräger, Eike Kunst, Hannah Benson, Florenz Sasse, Karsten Siems, Andreas Kirschning^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Research › peer review

Abstract

The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines.

Original language	English
Pages (from-to)	9040-9045
Number of pages	6
Journal	Organic and Biomolecular Chemistry
Volume	14
Issue number	38
DOIs	https://doi.org/10.1039/c6ob01697a
Publication status	Published - 2016

UN Sustainable Development Goals (SDGs)

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1039/c6ob01697a

Cite this

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title = "Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives",

abstract = "The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines.",

author = "Torsten Busch and Gerald Dr{\"a}ger and Eike Kunst and Hannah Benson and Florenz Sasse and Karsten Siems and Andreas Kirschning",

year = "2016",

doi = "10.1039/c6ob01697a",

language = "English",

volume = "14",

pages = "9040--9045",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "38",

}

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T1 - Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives

AU - Busch, Torsten

AU - Dräger, Gerald

AU - Kunst, Eike

AU - Benson, Hannah

AU - Sasse, Florenz

AU - Siems, Karsten

AU - Kirschning, Andreas

PY - 2016

Y1 - 2016

N2 - The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines.

AB - The synthesis of the diterpene (+)-tonantzitlolone A and a series of derivatives is reported. The study includes the determination of their antiproliferative activities against selected cancer cell lines.

UR - http://www.scopus.com/inward/record.url?scp=84989220466&partnerID=8YFLogxK

U2 - 10.1039/c6ob01697a

DO - 10.1039/c6ob01697a

M3 - Article

C2 - 27604289

AN - SCOPUS:84989220466

SN - 1477-0520

VL - 14

SP - 9040

EP - 9045

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 38

ER -

Synthesis and antiproliferative activity of new tonantzitlolone-derived diterpene derivatives

Abstract

UN Sustainable Development Goals (SDGs)

ASJC Scopus subject areas

Access to Document

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