The control of the consumer risk in the Ames assay

Markus Neuhäuser; Ludwig A. Hothorn

doi:10.1177/009286159703100207

The control of the consumer risk in the Ames assay

Markus Neuhäuser^*, Ludwig A. Hothorn

^*Corresponding author for this work

Department of Biostatistics

SOLVAY GmbH

Research output: Contribution to journal › Article › Research › peer review

Abstract

Preclinical tests in genetic toxicology represent safety studies. Therefore, the primary concern in the evaluation of Ames test data is the control of the consumer risk, that is, the risk of erroneously concluding safety. Hence, an equivalence test procedure is adequate. This approach is presented beside the two-fold rule and classical tests for differences with respect to an order restricted alternative.

Original language	English
Pages (from-to)	363-367
Number of pages	5
Journal	Drug Information Journal
Volume	31
Issue number	2
DOIs	https://doi.org/10.1177/009286159703100207 https://doi.org/10.15488/3052
Publication status	Published - 30 Dec 1997

UN Sustainable Development Goals (SDGs)

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Ames assay
Consumer risk
Difference approach
Equivalence test procedures for ordered many-to-one designs

ASJC Scopus subject areas

Pharmacology (nursing)
Drug guides
Public Health, Environmental and Occupational Health
Pharmacology (medical)

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10.1177/009286159703100207
10.15488/3052Licence: Other

Cite this

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The control of the consumer risk in the Ames assay

Abstract

UN Sustainable Development Goals (SDGs)

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this